Hundreds of digital health startups attended the recent HLTH conference in Las Vegas, seeking venture capital and insights. While many focused on similar areas like telehealth and chronic disease management, discussions revealed gaps in the market. Executives expressed interest in startups that could bridge academic research and commercialization, enhance patient engagement in daily health management, and integrate fragmented digital health solutions into cohesive platforms. They emphasized the need for technologies that keep patients engaged outside clinical settings and connect diverse healthcare stakeholders, particularly in complex areas like drug rebates. Opportunities remain for innovation in these underserved sectors.